Everything about the lab industry

Amerigo Scientific, a distribution company focused on providing critical products and services to the biomedical and life science research communities, now introduces soluble collagen that provides in-vivo-like conditions to positively influence adherence, growth, and differentiation of cells. The nature-like matrix to promote authentic cell performance is well suited for various applications, such as tissue engineering, and analysis of cell migration. Collagen is a well-known protein that has been widely used in biomedical research and development. 28 known types of collagen have been identified, which are extracellular and have a mainly structural role. It has various advantages as a biomaterial, one of which is that collagen demonstrates its ability to penetrate a lipid-free interface. The characteristics of collagen differ from those of synthetic polymers mainly in its mode of interaction in vivo. Compared with other natural polymers such as albumin and gelatin, collagen exhibits biodegradability, weak antigenicity, and superior biocompatibility. Soluble collagen is derived from bovine skin and can be used as a thin coating for 2D cell culture in any cell culture dish. For use in 3D cell culture, collagen hydrogels can be generated using standard protocols. The high collagen concentration of 5 mg/ml provides freedom to select the optimal gel density for cells. In addition, this flexible matrix may be mixed with factors like other ECM components, antibiotics, or growth factors, e.g. for directed cell manipulation. Supplemental cross-linking by the user is also feasible. Amerigo Scientific now offers soluble collagen for research uses such as tissue engineering e.g. of skin, osteogenic, endothelial, hepatocytic, and other tissues analysis of cell migration, e.g. at metastasis, wound healing, or development. "Our soluble collagen has benefits in many aspects, such as improvement of cell adherence, natural signals for cell growth, migration and differentiation, high concentration for flexible use, and long shelf life. In addition, our Collagen Cell Carrier is also available at Amerigo Scientific, which can be applied in tissue engineering and regenerative medicine," said Nina Cooper, Ph.D., the chief scientist at Amerigo Scientific. "We have a variety of talented and dedicated staff to help provide our biomedical and life science customers with critical products and services, and the release of this new soluble collagen to the scientific research community is a good example for that. It can be a very useful tool, and we are confident that the new offering will help enable us to continue to grow our business," added Nina. For more information about soluble collagen, please visit https://www.amerigoscientific.com. About Amerigo Scientific Amerigo Scientific is a distribution company that focuses on providing critical products and services to the biomedical and life science research communities. Although it is a new company, Amerigo Scientific's founder has had more than 20 years of rich experience in the biomedical and biochemical fields, and has established close contacts with key personnel in top international pharmaceutical and biotech companies, academic research institutes, and government research agencies. It has a professional team, as most of its employees own a graduate (Ph.D. or master) degree in life science, so they can understand customers' questions or concerns and are always ready to provide individualized customer service with high standard.

Amerigo Scientific, a distribution company focused on providing critical products and services to the biomedical and life science research communities, now introduces Human Pro-Glu-Plasminogen, Recombinant to the scientific community for various applications, such as coagulation research, medical research, protein structure, sequence analysis, and biochemical research. Proteins are used in a wide range of applications, such as functional assays, screening drugs, or Western Blot. Amerigo Scientific offers multiple types of highly purified proteins for researchers to meet any research needs, including high-quality purified membrane proteins involved in a wide range of diseases for many discovery programs, and membrane protein detergents and reagents for discovery projects to improve the poor solubilization rate and the weak stability of membrane proteins. More products such as the Barley albumin and globulin, KCC2 ion channel, Rye prolamin (Secalin), Corn prolamin (Zein), and Soy protein, an ethanol-soluble fraction are also available at Amerigo Scientific. This newly released human Pro-Glu-Plasminogen, recombinant is now accessible at Amerigo Scientific. It is noted that this new human Pro-Glu-Plasminogen, recombinant is intended for research use only, not for use in human, therapeutic or diagnostic applications, or food, drug, household, agricultural or cosmetic use. Its use must be supervised by a technically qualified individual experienced in handling potentially hazardous chemicals. Amerigo Scientific also recommends human Plasmin, recombinant and plasmin substrate Tosyl-GPKpNA, chromogenic for research usage. “Experimental results are critical for scientific studies. With Amerigo Scientific’s comprehensive proteins portfolio and other life science-related supplies, scientists can easily find what they need for their projects and gain more reliable data,” said Nina Cooper, Ph.D., the chief scientist at Amerigo Scientific. “This human Pro-Glu-Plasminogen, recombinant, and other recommended products combined with our life science expertise and capabilities will support customers in experimental trials in multiple areas. We will support our customers to make an achievement in their project by bringing a new offering to clients with exceptional speed, efficiency, and quality.” Amerigo Scientific specializes in the distribution of science supplies to customers and aims to integrate global superior product resources and technical resources to provide scientists with the latest, professional solutions. It assures that its manufacturers’ products are the most wanted for clients. For any of customers’ specific requirements, it guarantees to provide them with cutting-edge solutions and products and efficient services. For more information about the human Pro-Glu-Plasminogen, recombinant, please visit https://www.amerigoscientific.com. About Amerigo Scientific Amerigo Scientific is a distribution company that focuses on providing critical products and services to the biomedical and life science research communities. Although it is a new company, Amerigo Scientific’s founder has had more than 20 years of rich experience in the biomedical and biochemical fields, and has established close contacts with key personnel in top international pharmaceutical and biotech companies, academic research institutes, and government research agencies. It has a professional team, as most of its employees own a graduate (Ph.D. or master) degree in life science, so they can understand customers’ questions or concerns and are always ready to provide individualized customer service with high standard.

STEMart, a provider of integrated medical device CRO services dedicated to medical device and diagnostic clinical development, now launches risk assessments services for the medical device industry. It is used for the evaluation of potential risk problems that could be encountered in connection with the use of a medical device. Biological hazards, risk characterization, and toxicological risk assessment are required to ensure the safety of a novel medical device and meet the requirements of marketplaces. STEMart now offers a series of risk assessments services, including the Toxicological Risk Assessment, Biological Evaluation Plan, Biological Evaluation Report (BER), Equivalency Assessment, and Gap Analysis. For example, in terms of Toxicological Risk Assessment service, STEMart's expert team will help clients to use identified compounds and relevant biological testing to balance risks with the clinical benefit to the patient. It can provide hazard identification, dose-response evaluation, exposure assessment, and risk characterization. For Biological Evaluation Report, STEMart will help customers to determine various aspects, such as biological evaluation of the medical device, the acceptability of the material for the intended purpose, the risk management plan, material characterization, the interpretation of data and results, additional data for the biological evaluation, and biological safety conclusion. As for Biological Evaluation Plan (BEP), it is an initial risk assessment for medical devices. The general considerations for the BEP taken into account are the nature and duration of body contact, the selection and materials of construction, manufacturing processes, the biological endpoints of concern, and the historical use of the device. BEP supports a strategy to address areas of remaining biological risk, which may include both chemical and biological testing. This new series of risk assessments services is a supplement to the biocompatibility testing services. STEMart offers comprehensive biocompatibility testing for both in vitro and in vivo assessments. With extensive expertise in biocompatibility testing, STEMart can provide a full-service experience, support manufacturers to meet the regulatory goals, and minimize the compliance risks. Its experts have years of experience in a variety of testing services for Class, I, II, and III medical devices, and can provide assistance for customers to ensure that every aspect of the medical device is properly inspected. "We are glad to offer such a new series of risk assessments services to the medical device industry. Our team has considerable experience and looks forward to working with our clients. We will continue our commitment to providing high-quality service and useful tools for the institutions and organizations we serve," said Tina Frederick, Executive Director of Marketing at STEMart. If you have additional questions about medical device risk assessments services or would like to find out more about the medical device development service, please visit https://www.ste-mart.com. About STEMart STEMart is an industry-leading eCommerce platform with an expanded global footprint and has a broad portfolio of more than 10,000 products. It aims to provide best-in-class lab materials, medical instruments and consumables, excellent technologies, and high-quality services to global customers in the fields of science, technology, and engineering, from the discovery stage towards the manufacturing process. STEMart is dedicated to making research and biotech production simpler and safer, and through that to accelerate access to better health for people everywhere.

CD Bioparticles, a leading manufacturer and supplier of various drug delivery products and services, now introduces a series of customizable MOFs linkers that can be used as monomers to synthesize MOF materials. CD Bioparticles offers various Porous Organic Materials for researchers, such as the RAFT Reagents, MOF Initiators, Functional Materials, Catalyst & Ligands, Metal-organic Frameworks (MOFs) Linkers, and MOFs Materials. These newly released customizable MOFs linkers are an expansion of the MOFs linkers products. Now the new customizable MOFs linkers such as thieno[3,2-b]thiophene-2,4-dicarboxylic acid, tri (pyridin-3-yl)amine, [1,1'-Biphenyl]-2,2',4,4',6,6'-hexacarboxylic acid, and [1,1': 3',1''-Terphenyl]-2,2''-dicarboxylic acid, 5'-(2-carboxyphenyl)- are all available at CD Bioparticles. In addition, CD Bioparticles is capable of providing customized MOFs with various material formats and chemical compositions. It can help the science community to solve challenges that they might meet, such as limited MOF options in the market for different applications, restricted surface area, limited facilities for large production yield with consistent quality control, low production yield, and low consistency, or tedious processing and formulation. "AS a professional supplier of MOFs linkers, we can ensure the quality of our MOFs products. CD Bioparticles can provide our customers with a wide coverage of the MOFs and free choice of building blocks. And we can guarantee cost-effective MOF manufacturing at scale, with tailored textural properties. We can also promise you the supply of highly-porous, suitably robust, shaped MOFs that are tailored to your applications, such as membrane separation, sensors, and biotech." said Dr. Robin J. Watts, the scientific officer of the R&D department of CD Bioparticles. Metal-organic frameworks are constructed from metal ions/clusters coordinated by organic linkers (or bridging ligands). In addition to the MOFs materials, CD Bioparticles also provides Hydrogen-bonded Organic Framework (HOF) Materials, which can be applied for gas adsorption and separation, drug delivery for large drug molecules or enzymes or RNA, and Covalent Organic Framework (COF) Materials that can be used for gas adsorption and separation, and catalyst support. "MOFs have attracted scientists for bio-applications. The MOFs linkers expansions provide our customers with access to CD Biopartciles MOFs-related offerings, and we are thrilled to release this new one and expand new technology. We'll focus on our mission to support our academic and medical clients, and continue our commitment to providing our customers with drug delivery solutions through all stages of the development process, as well as continuing to work with our partners and scientific researchers globally to accelerate their discoveries." added Robin. For other detailed information on customizable MOFs linkers, please visit CD Bioparticles at https://www.cd-bioparticles.net. About CD Bioparticles CD Bioparticles is an established drug delivery company that provides customized solutions for developing and producing new, biocompatible drug delivery systems. It specializes in a range of formulation and drug delivery technologies, from conventional liposomes, PEGylated liposomes for drug delivery to polymer microspheres and nanoparticles for enhanced drug delivery. It provides contract services of drug delivery formulation developments for basic research, formulation feasibility studies, process development, and scale-up, formulation characterization, analytical and non-clinical services.

With years of experience in the pharmaceutical and life science sector, CD Bioparticles now launches a series of highly-monodisperse spherical titania nanoparticles (Titania Aqueous Dispersion and Titania Ethanol Dispersion). These novel products offer unique properties such as high dielectric constant (95-105) and high refractive index (2.488) and can be utilized in dye sensitized solar cells, lithium-ion batteries, bioanalysis, biosensing technologies and photonic crystals. Despite Titanium dioxide (TiO2) nanoparticles being widely available, there is currently rare commercial source for monodisperse non-aggregated TiO2 nanoparticles. CD Bioparticles' particles are monodispersed, un-agglomerated, and have well-defined sizes and morphologies. The unique morphology and homogeneity of the titania nanoparticles makes them ideal for use in a variety of applications, including photocatalysis, photovoltaics, chromatography, self-cleaning surfaces, advanced pigments and cosmetics and high refractive index optical coatings. In this release, the particle sizes available are between 100 and 900 nm, with low coefficient of variation (CV<15%), unique among other products that are currently available on the market. These new spherical titania nanoparticles can be supplied as aqueous or ethanol suspensions in a range of concentrations (2.5-10wt%). Various products such as DiagNano™ Titania Aqueous Dispersion, 100 nm, and DiagNano™ Titania Ethanol Dispersion, 150 nm are all available at CD Bioparticles. "The new release of these spherical titania nanoparticles not only demonstrates our manufacturing capabilities, but also shows our commitment to providing high quality nanoparticles products to our global customers. We'll increase our product capacity and help address growing customer demand for nanoparticles product solution in both research and industrial development." said Dr. Jessica Waldorf, chief scientific officer of R&D department, at CD Bioparticles. "Through the expansion of our nanoparticles products and services, we will have the capability to support our clients to accelerate research in immunoassay, bioseparation, medical imaging and diagnosis, as well as drug delivery and cancer therapy." In addition, CD Bioparticles also offers a variety of precisely engineered titanium dioxide nanoparticles with uniform size and shapes. Different crystal forms including amorphous, anatase and rutile titania nanoparticles are provided both in nanopowder and dispersion. These titania nanoparticles have wide size range from 5 nm to 500 nm. Surface functionalized titania particles are also available for covalent conjugation with proteins, antibodies and other biomolecules. The titania nanoparticles can be applied in skin products, additives, foods, air cleaning due to its strong UV absorption and active photocatalytic properties. CD Bioparticles provides highly uniform nanoparticles widely used in biology and medicine. These nanoparticles are manufactured with different shapes and sizes, and the particle surface can be coated, functionalized or conjugated with biomolecules. For more detailed information about spherical titania nanoparticles or to discuss your project, please visit CD Bioparticles at https://www.cd-bioparticles.com. About CD Bioparticles CD Bioparticles is a global leading manufacturer and supplier of various nanoparticles, microparticles and their coatings for R&D and commercialization in a wide variety of application areas including in vitro diagnostics, biochemistry, cellular analysis, cell separation, and immunoassay. It also offers various custom services including chemical surface-functionalized, fluorescent modification, antibody immobilization, nucleic acid and oligo conjugation to meet clients' specifications.