Phage display was first devised in 1985 as a method for displaying polypeptides on the surface of lysogenic filamentous bacteriophages. This technology has become one of the most effective ways of generating considerable quantities of peptides, proteins, and antibodies. By displaying peptides, antibodies, or proteins on the surface of a bacteriophage, researchers can couple genotype to phenotype, providing the ability to quickly screen billions of different clones. The sheer amount of diversity increases the chance of finding rare binders with exceptional specificity and affinity.
“Phage display enables us to interrogate molecular interactions on a scale that would have been unimaginable in the recent past,” said an immunologist at Creative Biolabs. “With many years of experience, our scientists have developed a number of phage display based platforms and customized hundreds of specific libraries and thousands of specific antibody products to accelerate the research and project goals of our global customer base.”
Creative Biolabs has positioned itself as a leading phage display library construction service provider, offering scFv, Fab, and VHH formats.
At Creative Biolabs, they build antibody, peptide, scaffold, and cDNA libraries to provide researchers with access to myriad platforms for drug discovery, biomarker discovery, and protein interaction studies.
But library building is only half the story. Screening is what turns the library into something of value. That’s why Creative Biolabs offers phage display library screening services using state-of-the-art biopanning strategies and customized protocols. Using solid-phase, solution-sorting, cell-based, in vivo, and ex vivo screening approaches, their scientists enrich binders to 10⁻⁹ or even 10⁻¹² affinity.
This flexibility means researchers can screen against purified proteins, intact cells, or tissues in living organisms. And by combining proprietary protocols with next-generation sequencing and biophysical assays, Creative Biolabs ensures your screened candidates are optimized for functionality and specificity in addition to high affinity.
Creative Biolabs also offers premade library licensing services for projects that call for speed. Available human, mouse, rabbit, chicken, camelid VHH, and synthetic repertoires are thoroughly validated for diversity and functionality in the premade libraries.
Premade libraries can be instantly incorporated into a discovery pipeline—saving you time and money by sparing you the time-consuming processes of immunization and building.
“Time is the most precious commodity in biotech,” said the leading scientist at this company. “Premade libraries from Creative Biolabs give teams a head start, letting them focus on innovation rather than infrastructure.”
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About Creative Biolabs
With over 20 years of expertise, Creative Biolabs combines cutting-edge technology, tailored strategies, and global support to advance research. Whether constructing a custom phage display library, screening for high-affinity binders, or licensing premade solutions, their services empower scientists to accelerate therapeutic development, diagnostics, and fundamental discoveries.
Discovery Premade Libraries
