Fc Fusion Protein Production Service Now Available at Profacgen

29 March 2022
Article image of: Fc Fusion Protein Production Service Now Available at Profacgen

Profacgen, a state-of-the-art protein service provider located in the USA, provides comprehensive one-stop services for pre-clinical drug development, aiming to evaluate and improve the efficacy and safety of new drug candidates. Now, Profacgen can provide soluble Fc fusion protein to applicate in various fields.

Fc fusion protein refers to a new type of protein produced by using genetic engineering technology to fuse the downloaded Fc segment of immunoglobulin (IgG, IgA, etc.) with a certain biologically active functional protein molecule. Functional proteins with biological activity can be cytokines, toxins, receptors, enzymes, antigenic peptides and the like. Fc fusion protein not only exerts the biological activity of the fusion protein, but also has some antibody properties, such as antibody-dependent cell-mediated cytotoxicity (ADCC), complement-dependent cytotoxicity (CDC) and antibody-dependent cell-mediated phagocytosis (ADCP).

Protein drugs have a short half-life in plasma, and in order to achieve a therapeutic effect, large doses are required, which will cause serious side effects and cause a huge burden to patients. The fusion of functional protein with the Fc segment of immunoglobulin can prolong the half-life of the drug in plasma and reduce the immunogenicity of the drug, which is of great significance in the diagnosis and treatment of diseases.

Profacgen is committed to providing comprehensive one-stop services for preclinical drug development, including global pharmacology/toxicity research and chemistry, manufacturing, and control (CMC) services. With the effort of scientists at Profacgen, the company now provides soluble Fc fusion protein to applicate in various fields, including immunotherapy, non-clinical fields (flow cytometry, immunohistochemistry), in vitro activity detection and protein microarray detection with the deepening of research.

Based on the information from Profacgen.com, the newly launched services include: N-term or C-term of Fc fused with single peptides, enzymes, antigens, receptors, ligands, cytokines, etc. “Supported by our extensive experience in drug delivery study, we can provide gene synthesis, Fc fusion protein expression, purification and validation.” Said Crystal, the chief marketing staff at Profacgen.

To see more detail about the Fc fusion protein production service provided by Profacgen, please visit https://www.profacgen.com/fc-fusion-protein-production-service.htm.

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