The global market for research antibodies is expected to reach
$3 billion in 2019. Selecting the right antibody that works for your specific assay is a daunting process that is often fraught with failure. A Nature article estimates that half of all of antibodies are considered bad. Bad antibodies are often the product of research that is not reproducible and certainly contributes to wasted research resources.
Good Antibodies Make Great Assays
For the successful use of an antibody on any platform, the method of antibody generation is an important consideration. Monoclonal antibodies are produced from hybridoma cell lines, whereas polyclonal antibodies are harvested from animal serum. Recombinant antibodies are more reliable compared to their monoclonal and polyclonal counterparts because they are made from cultured cell lines carrying an expression plasmid DNA or other expression construct.
