Pharmaceutical Potential of N-Benzylhydroxylamine Hydrochloride (CAS 29601-98-7)

N-Benzylhydroxylamine Hydrochloride | Photo: Hunan Huateng Pharmaceutical

Hunan Huateng Pharmaceutical Co., Ltd., a leading global supplier of PEG derivatives and pharmaceutical intermediates, is proud to offer high-purity N-Benzylhydroxylamine Hydrochloride (CAS 29601-98-7) to researchers and pharmaceutical developers worldwide. This compound has gained attention for its multifunctional properties and critical role in drug discovery and development.

N-Benzylhydroxylamine Hydrochloride features a unique nitrogen–oxygen (N–O) functional group, which enables its wide-ranging applications in medicinal chemistry, including:

• Metal Chelation for Iron Overload Disorders: Its ability to form stable complexes with metal ions like Fe³⁺ and Cu²⁺ makes it a promising candidate for addressing metal-induced toxicity, particularly in diseases such as β-thalassemia.
• Key Intermediate in HDAC Inhibitor Synthesis: This compound plays a crucial role in synthesizing hydroxamic acid-based histone deacetylase (HDAC) inhibitors, such as Vorinostat, an FDA-approved cancer therapy.
• Potential MAO Inhibition: Its structure suggests possible use in developing monoamine oxidase (MAO) inhibitors, which are important in treating depression and neurodegenerative diseases.
• Antioxidant Properties: N-Benzylhydroxylamine Hydrochloride exhibits free radical scavenging activity that may help mitigate oxidative stress implicated in Alzheimer’s, Parkinson’s, and cardiovascular conditions.
• Antibacterial and Antiviral Applications: By chelating essential metal ions, it may inhibit bacterial growth and interfere with metal-dependent viral replication mechanisms.
• NOS Modulation: Its potential to regulate nitric oxide synthase (NOS) activity presents an intriguing opportunity for managing inflammation and cardiovascular health.

The compound is also widely used as an intermediate in organic synthesis, serving as a protective group for amines and facilitating the development of structurally complex molecules.

“We are dedicated to providing high-quality chemical building blocks like N-Benzylhydroxylamine Hydrochloride to accelerate innovation in drug development,” said Jack Deng, CEO of Huateng Pharma. “We believe our commitment to quality and customer support will empower researchers and companies to achieve their pharmaceutical goals more efficiently.”

About Huateng Pharma

Hunan Huateng Pharmaceutical Co., Ltd. is a world-leading supplier of PEG derivatives and pharmaceutical intermediates, offering R&D-to-commercial scale support for global biopharmaceutical customers. Our advanced manufacturing facilities and comprehensive product portfolio help accelerate drug development and deliver innovative healthcare solutions.