Creative Biostructure, a biotech company specialized in providing cost-effective contract services related to structural biology and membrane protein technologies to both academia and biotech/pharmaceutical industries, now released target 3D structure analysis service for drug discovery.
Target structure information can be used in multiple links of drug discovery, such as target selection, identification and optimization of hit points, development of final properties of compounds using multithreading processes and reconstruction of biological macromolecular structures by rational design to optimize their structural druggability. Moreover, the high drug consumption rate associated with clinical trials in the late stages of drug development is an important reason for the rising cost, which further promotes the need to obtain accurate target three-dimensional (3D) structural information to reduce the possibility of drug failure.
Using extensive expertise in structural biology and in silico drug design, Creative Biostructure supports various experimental techniques to determine the structure, such as X-ray crystallography, cryo-electron microscopy, NMR spectroscopy, etc. Many problems have been solved through Creative Biostructure’s gene-to-gene and gene-to-structure services in the field of membrane proteins and structural biology for customers all over the world.
Features of Creative Biostructure’s 3D structure analysis service
•Comprehensive target-based structural biology platform, covering cutting-edge and mainstream technologies for 3D structural analysis
•Experience in solving difficult structural challenges, such as membrane proteins, large multi-subunit complexes, kinases, phosphatases and epigenetic proteins
•Tailored structure analysis strategy for the target protein to meet the exact needs of customers
•In-house developed high-quality drug target proteins and crystal structures for analysis
“We feel quite honored for the release of novel 3D structure analysis service. We are quite sure that we can successfully predict the affinity and binding patterns of receptors and ligands with our 10 years of experience in structure-based drug discovery.” Commented Joanna, the chief marketing staff at Creative Biostructure.
Moreover, Creative Biostructure has established the target-based structural biology platform, computer-aided drug design (CADD) platform, and fragment-based drug design (FBDD) platform for structure accelerated drug discovery.
For more information, please visit Creative Biostructure
Our solutions of structure-based drug discovery cover the full range of customer needs for early-stage drug discovery, including but not limited to, target protein structure research, lead discovery and optimization, structure-based biological drug discovery, and biosimilars structure characterization. Moreover, we can provide a comprehensive list of promising and customizable drug target proteins, protein crystals, and other related products to assist customers to conduct structure-based drug screening.
