Scientists in the field of protein engineering and analysis now have access to the newly updated de novo protein design service, an attractive approach for constructing designed proteins with predetermined structures and functions.
The process of protein molecular design mainly relies on the determination of protein structure and the establishment of molecular models. According to the relationship between protein structure and function, the technical methods of various disciplines are comprehensively used to ensure that new proteins with better performance than natural proteins can be obtained. The amino acid residues on natural protein molecules with a known structure can be used to study and improve the properties and functions of proteins; it is also possible to splice and assemble the domains of different proteins from different sources to transfer the corresponding functions, thereby obtaining protein molecules with new characteristics; It is possible to design a completely new protein from scratch to make it have a specific spatial structure and expected function. Different from the “small changes” and “medium changes” in the first two types of protein design, designing a completely new protein from scratch is a “big change” to the protein molecule, and it must have a specific spatial structure and expected function. It is also regarded as an unrealized worldwide problem, and this difficult barrier between biomedicine and protein structure is gradually being dismantled by the team of talented scientist David Baker.
Although the de novo protein design has been greatly developed in recent years, it is still a very difficult challenge for newcomers to protein de novo design, because the design of a new protein structure requires professional knowledge and rich creativity and intuition. This is something that computers cannot fully realize.
Over the years, scientists from Creative Biostructure have been actively working on the characterization of proteins using a variety of techniques, as well as the engineering of proteins for various applications. The extensive experience gained in these areas enable it to provide customized services in a timely and cost-effective manner.
Creative Biostructure provides de novo design related services for protein engineering, including protein structure prediction, protein folding and interactions, thermodynamics information, energetic state, stability, etc.
“With a full understanding of various techniques and the requirements of every client, we will select appropriate strategies to assist your protein analysis project.” Commented Joanna, the chief marketing staff at Creative Biostructure.
If you’d like to know more about the de novo protein design service offered by Creative Biostructure, please visit Creative Biostructure
Creative Biostructure is specialized in providing contract services to both academia and biotech/pharmaceutical industries in the field of structural biology. The company offers insightful strategies and cost-effective services on structure determination of macromolecules using X-ray Crystallography, EM, NMR, etc.
